Unfortunately, there is currently no cure for lycanthropy. However, some of the worst effects can be mitigated by consuming Wolfsbane Potion, which allows a werewolf to retain his or her human mind while transformed, thus freeing him or her from the worry of harming other humans or themselves. It is a very difficult potion to make, with many complicated ingredients. According to Remus Lupin, it tastes disgusting but sugar makes it useless. The expensiveness of the ingredients makes it virtually impossible for werewolves to brew the potion for themselves, as most are reduced to poverty and cannot taste the potion without revealing their statuses. Because werewolves only pose a danger to humans, companionship with animals whilst transformed has been known to make the experience more bearable as the werewolf has no-one to harm and will be less willing to harm themselves.

According to Gilderoy Lockhart, the Homorphus Charm can force a werewolf back into human shape. However, due to Lockhart's reputation as a liar, and the many falsehoods he told to inflate his popularity, his information is highly suspect — as is the very existence of a Homorphus Charm in the first place. However, as many of Lockhart's claims are also based on the accounts of more trustworthy wizards (accomplishments he would claim for himself, following the disposal of the originating witch or wizard), there is a chance that the charm does, in fact, exist.

Contrary to what the Muggle world believes, werewolves are not affected by silver, except in that it can be used in the mixture of powdered silver and dittany to prevent death and merely closes their wounds to prevent bleeding in a severe werewolf attack. There may certainly be several other ways and solutions to prevent and heal werewolf injuries, as Quirinus Quirrell taught about the topic in first year Defence against the Dark Arts class. None of them, of course, could completely cure an afflicted person once they are bitten, but can merely prevent and close the physical wounds on the skin.